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Study identifier: NCT06311227 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Venetoclax for the Treatment of Patients With Relapsed Hairy Cell Leukemia

Condition: Recurrent Hairy Cell Leukemia · Recurrent Hairy Cell Leukemia Variant  ·  Sponsor: National Cancer Institute (NCI)

PhasePhase 2
Planned participants20
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This phase II trial tests how well venetoclax works in treating patients with hairy cell leukemia that has come back after a period of improvement (relapsed). Venetoclax is in a class of medications called B-cell lymphoma-2 (BCL-2) inhibitors. It may stop the growth of cancer cells by blocking Bcl-2, a protein needed for cancer cell survival.

This description comes directly from the study's public registry record.

Talk to the study team

Contact details are listed per location below or on the registry record.

Always discuss trial participation with your own doctor first.

Locations (21)

City of Hope Comprehensive Cancer CenterDuarte, California, United StatesSuspended
City of Hope at Irvine LennarIrvine, California, United StatesSuspended
UM Sylvester Comprehensive Cancer Center at AventuraAventura, Florida, United StatesRecruiting
UM Sylvester Comprehensive Cancer Center at Coral GablesCoral Gables, Florida, United StatesRecruiting
UM Sylvester Comprehensive Cancer Center at Coral SpringsCoral Springs, Florida, United StatesRecruiting
UM Sylvester Comprehensive Cancer Center at Deerfield BeachDeerfield Beach, Florida, United StatesRecruiting
UM Sylvester Comprehensive Cancer Center at DoralDoral, Florida, United StatesRecruiting
UM Sylvester Comprehensive Cancer Center at HollywoodHollywood, Florida, United StatesRecruiting
University of Miami Miller School of Medicine-Sylvester Cancer CenterMiami, Florida, United StatesRecruiting
UM Sylvester Comprehensive Cancer Center at KendallMiami, Florida, United StatesRecruiting
University of Kansas Cancer CenterKansas City, Kansas, United StatesRecruiting
University of Kansas Cancer Center-Overland ParkOverland Park, Kansas, United StatesRecruiting

+ 9 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06311227