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Study identifier: NCT06310291 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

VTP-1000 in Adults With Celiac Disease

Condition: Celiac Disease  ·  Sponsor: Barinthus Biotherapeutics

PhaseEARLY_Phase 1
Planned participants45
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

About this study

GLU001 is a first-in-human clinical trial to assess the safety and tolerability of VTP-1000 for adults with celiac disease. This trial will assess VTP-1000 at various dose levels compared to placebo in a single ascending dose (SAD) and multiple ascending dose (MAD) format. Participants will be followed for a short period of time to assess the impact of VTP-1000 on their immune system (Adverse events, reactions in the blood, and physical exam differences). Participants enrolled in the MAD portion of the trial will undergo a gluten challenge to assess the impact exposure to gluten has on participants after administration of VTP-1000.

This description comes directly from the study's public registry record.

Talk to the study team

Contact details are listed per location below or on the registry record.

Always discuss trial participation with your own doctor first.

Locations (16)

Parexel EPCU LALos Angeles, California, United StatesRecruiting
Peak Gastroenterology AssociatesColorado Springs, Colorado, United StatesRecruiting
Jacksonville Center for Clinical ResearchJacksonville, Florida, United StatesRecruiting
GCP ResearchSt. Petersburg, Florida, United StatesRecruiting
Parexel EPCU BaltimoreBaltimore, Maryland, United StatesRecruiting
Clinical Research Institute of MichiganClinton Township, Michigan, United StatesRecruiting
West Michigan Clinical Research CenterWyoming, Michigan, United StatesRecruiting
Mayo ClinicRochester, Minnesota, United StatesRecruiting
NYU Langone - Gastroenterology AssociatesNew York, New York, United StatesRecruiting
North Carolina Clinical ResearchRaleigh, North Carolina, United StatesRecruiting
Centricity ResearchColumbus, Ohio, United StatesRecruiting
Vanderbilt University Medical CenterNashville, Tennessee, United StatesRecruiting

+ 4 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06310291