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Study identifier: NCT06308419 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Phase I Trial of Combination Gemcitabine and Nab-Sirolimus in Advanced Leiomyosarcomas or Advanced Soft-Tissue Sarcomas With TSC2 or TSC1 Loss-of-function Mutations or Deletions

Condition: Leiomyosarcoma · Soft-tissue Sarcomas  ·  Sponsor: M.D. Anderson Cancer Center

PhasePhase 1
Planned participants18
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

To find a recommended dose of gemcitabine and nab-sirolimus that can be given in combination to participants with advanced leiomyosarcomas or soft-tissue sarcomas.

This description comes directly from the study's public registry record.

Talk to the study team

Elise Nassif, MD  ·  (281) 460-0607  ·  efnassif@mdanderson.org

Gracy Zacharian, BSN,MSN,RN  ·  (713) 792-2669  ·  gzachari@mdanderson.org

Always discuss trial participation with your own doctor first.

Locations (1)

MD Anderson Cancer CenterHouston, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06308419