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Study identifier: NCT06308172 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Impact of Single- Versus Double-layer Hysterotomy Closure on Cesarean Niche Development: a Randomized Controlled Trial

Condition: Cesarean Section; Dehiscence · Uterine Bleeding · Uterus; Scar  ·  Sponsor: Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico

PhaseNA
Planned participants150
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

The objective of this randomized monocentric study is to assess potential variations in the incidence and severity of isthmocele morbidity among women undergoing cesarean section with either single or double-layer closure of the hysterotomy. Our primary outcome aims to investigate whether there is a reduction in the median duration of intermenstrual spotting in patients belonging to the two respective closure groups

This description comes directly from the study's public registry record.

Talk to the study team

Giuseppe Perugino, MD  ·  3383030553  ·  giuseppe.perugino@policlinico.mi.it

Always discuss trial participation with your own doctor first.

Locations (1)

Fondazione Cà Granda IRCCS Ospedale Maggiore Policlinico di MilanoMilan, Mi, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT06308172