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Study identifier: NCT06306443 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Buprenorphine for Individuals in Jail

Condition: Opioid Use Disorder  ·  Sponsor: Friends Research Institute, Inc.

PhasePhase 3
Planned participants240
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

This study is an open label randomized controlled trial of extended-release buprenorphine (BRIXADI, XR-B) vs. sublingual buprenorphine (SL-B) in a large metropolitan jail. An open-label design will randomly assign 240 adults with moderate-to-severe OUDs who are soon-to-be-released from jail to either XR-B (n=120) or SL-B (n=120) treatment in jail followed by 6-months of post-release buprenorphine treatment, a 7-month safety visit, and a final long-term follow-up at 12-months.

This description comes directly from the study's public registry record.

Talk to the study team

Michael Gordon, DPA  ·  4108373977  ·  mgordon@friendsresearch.org

Thomas R Blue, PhD  ·  4108373977  ·  tblue@friendsresearch.org

Always discuss trial participation with your own doctor first.

Locations (2)

Friends Research InstituteBaltimore, Maryland, United StatesRecruiting
Baltimore Central Booking & Intake CenterBaltimore, Maryland, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06306443