Condition: Pain, Acute · Sponsor: Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Musculoskeletal (MSK) injuries such as sprains, strains, bruises, and fractures are among the most common reasons people visit the emergency department. These injuries often cause significant pain in the first few days, making it difficult to move, work, or sleep. Usual pain medications like ibuprofen or acetaminophen can help, but they are not safe or effective for everyone. Some people cannot take them because of heart, kidney, stomach, or liver problems. Others still experience strong pain despite treatment. Because of these limits, some patients receive opioids, which can cause side effects and carry a risk of dependence. Safer and more accessible options are needed. Vitamin C is widely known for supporting the immune system, but research suggests it may also help reduce pain and inflammation. Studies in surgical patients have shown that vitamin C can lower pain levels, reduce the need for opioids, and support healing. These effects may be linked to its antioxidant properties and its role in tissue repair. However, no study has tested whether vitamin C can help people with recent MSK injuries treated in the emergency department. The VICAMED study aims to answer this question. Adults arriving with an MSK injury that occurred within the past 48 hours can participate if they have at least moderate pain. Participants are randomly assigned to receive either vitamin C or a placebo. The first dose is given in the emergency department, followed by twice daily capsules for three…
This description comes directly from the study's public registry record.
Martin Marquis, MSc · 514-338-2222 · martin.marquis.cnmtl@ssss.gouv.qc.ca
Always discuss trial participation with your own doctor first.
| The Ottawa Hospital - General and Civic Campus | Ottawa, Ontario, Canada | Not Yet Recruiting |
| Hôtel-Dieu de Lévis | Lévis, Quebec, Canada | Not Yet Recruiting |
| Hopital du Sacre-Coeur de Montreal | Montreal, Quebec, Canada | Recruiting |
| CHU de Québec - Université Laval | Québec, Quebec, Canada | Not Yet Recruiting |
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Source record: clinicaltrials.gov/study/NCT06306183