← Eichor
Study identifier: NCT06305234 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Long Term, Post-marketing Study of Immune Response in Patients Receiving Palynziq Treatment for PKU (PALisade)

Condition: Phenylketonuria (PKU)  ·  Sponsor: BioMarin Pharmaceutical

PhaseN/A
Planned participants200
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNo

About this study

This is a 10-year multi-center, prospective, longitudinal, single arm study evaluating immunologic, inflammatory and laboratory parameters associated with long-term Palynziq treatment in subjects with phenylketonuria (PKU) in the United States (US). Subjects in the US for whom a clinical decision has been made that they will receive pegvaliase to treat their PKU within 30 days following the date of enrollment in Study 165-501 (incident-users) or who have previously started treatment with pegvaliase at the date of enrollment in Study 165-501 (prevalent-users) are eligible for participation in Study 165-503.

This description comes directly from the study's public registry record.

Talk to the study team

165-503 Program Director  ·  1-800-983-4587  ·  medinfo@bmrn.com

Medical Director, MD  ·  1-800-983-4587  ·  medinfo@bmrn.com

Always discuss trial participation with your own doctor first.

Locations (11)

University of ColoradoAurora, Colorado, United StatesRecruiting
Emory UniversityAtlanta, Georgia, United StatesRecruiting
Northwestern UniversityChicago, Illinois, United StatesRecruiting
Riley Children's Hospital/ Indiana University HealthIndianapolis, Indiana, United StatesRecruiting
Tulane University School of MedicineNew Orleans, Louisiana, United StatesRecruiting
Boston Children's HospitalBoston, Massachusetts, United StatesRecruiting
Oregon Health & Science UniversityPortland, Oregon, United StatesRecruiting
University of Pittsburgh Medical CenterPittsburgh, Pennsylvania, United StatesRecruiting
Vanderbilt University Medical SchoolNashville, Tennessee, United StatesRecruiting
UT Southwestern Medical CenterDallas, Texas, United StatesRecruiting
Children's Wisconsin/Medical College of WisconsinMilwaukee, Wisconsin, United StatesRecruiting

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT06305234