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Study identifier: NCT06304350 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Pembrolizumab Combined With Preoperative Chemotherapy (Albumin Paclitaxel+Carboplatin) Neoadjuvant Therapy for Resectable Locally Advanced (Stage II/III) Esophageal Squamous Cell Carcinoma

Condition: Esophageal Cancer  ·  Sponsor: Tongji University

PhasePhase 2
Planned participants25
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This study is a prospective, single center, open label, single arm clinical study. Select resectable locally advanced (cT3-4aN0M0, cT1-3N1-2M0, cII/III stage) esophageal cancer with pathological diagnosis of squamous cell carcinoma for inclusion, receive pembrolizumab combined with platinum containing dual drug (albumin paclitaxel+carboplatin) treatment for 2 courses, and undergo surgery. After surgery, continue pembrolizumab immunotherapy. Using pCR as the main endpoint of the study

This description comes directly from the study's public registry record.

Talk to the study team

Jiang Fan, MD  ·  15901013210  ·  fan_jiang@tongji.edu.cn

Fu Yang, DM  ·  18101839885

Always discuss trial participation with your own doctor first.

Locations (1)

Shanghai General HospitalShanghai, Shanghai Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06304350