Condition: Penicillin Allergy · Sponsor: James Tarbox, MD
The goal of this clinical trial is to learn about dosing when testing to see if a penicillin allergy label can be removed from adults that had been labeled as "penicillin-allergic" previously. The main question it aims to answer is: \- In penicillin-allergic patients that are at low risk of having an allergic reaction, is a one-dose oral challenge with amoxicillin (a penicillin-based antibiotic) as safe and effective as a two-dose oral challenge? Participants will, after being identified as having a low-risk penicillin allergy, be administered oral amoxicillin in a controlled setting and then monitored for an allergic reaction. Researchers will compare participants that took one dose of amoxicillin to participants that took two doses of amoxicillin (a small dose and then a larger dose) to see if either group was more likely to develop an allergic reaction.
This description comes directly from the study's public registry record.
Study Coordinator · 806-543-8994 · clinicalresearch@ttuhsc.edu
Joshua A Peterson, MD · josh.peterson.587@gmail.com
Always discuss trial participation with your own doctor first.
| Texas Tech University Health Sciences Center | Lubbock, Texas, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06303128