Condition: Colorectal Cancer Metastatic · Liver Metastases · Colorectal Cancer · Sponsor: Weill Medical College of Cornell University
The goal of this clinical trial is to to learn about different combinations of immunotherapy in patients with colorectal cancer whose cancer has spread to their liver and are planning to have surgery to remove tumor metastases from their liver. The main questions it aims to answer are: * whether these combinations of immunotherapy change the tumor microenvironment in the liver * whether these combinations of immunotherapy are safe and effective when used in colorectal cancer with liver metastases Participants will be randomly assigned to one of the following: * Botensilimab and balstilimab * Botensilimab, balstilimab, and AGEN1423 * Botensilimab, balstilimab, and radiation Participants will be asked to come in to receive drug infusions (and radiation, if applicable) before and after their surgical resection. Participants will be followed for up to 2 years.
This description comes directly from the study's public registry record.
Casey Owens · 646-962-6046 · cdo4001@med.cornell.edu
Myriam Elizaire-Williams · mye4001@med.cornell.edu
Always discuss trial participation with your own doctor first.
| Weill Cornell Medicine/NewYork-Presbyterian Hospital | New York, New York, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06300463