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Study identifier: NCT06300177 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

D-1553 Tablet Versus Docetaxel Injection for KRAS G12C Mutation-positive Locally Advanced or Metastatic Non-small Cell Lung Cancer After Prior Standard Therapy Failure

Condition: Non Small Cell Lung Cancer  ·  Sponsor: Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

PhasePhase 3
Planned participants522
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this project is to evaluate progression-free survival (PFS) of D-1553 Tablet versus Docetaxel Injection in subjects with prior standard therapy failure kirsten rat sarcoma viral oncogene (KRAS) G12C mutation positive locally advanced or metastatic non small cell lung cancer (NSCLC), progression-free survival (PFS) as assessed by the Independent Review Committee (IRC) based on RECIST 1.1 was used as the primary endpoint.

This description comes directly from the study's public registry record.

Talk to the study team

Shun Lu, Doctor  ·  13601813062  ·  shun_lu@hotmail.com

Always discuss trial participation with your own doctor first.

Locations (86)

Anhui Province HospitalHefei, Anhui, ChinaNot Yet Recruiting
Cancer Hospital Chinese Academy of Medical SciencesBeijing, Beijing Municipality, ChinaNot Yet Recruiting
Xuanwu Hospital Capital Medical UniversityBeijing, Beijing Municipality, ChinaNot Yet Recruiting
Beijing Cancer HospitalBeijing, Beijing Municipality, ChinaNot Yet Recruiting
Peking University Third HospitalBeijing, Beijing Municipality, ChinaNot Yet Recruiting
Beijing Chest Hospital,Capital Medical UniversityBeijing, Beijing Municipality, ChinaNot Yet Recruiting
The Fifth medical center of Chinese PLA General HospitalBeijing, Beijing Municipality, ChinaNot Yet Recruiting
The Second Affiliated Hospital of Chongqing Medical UniversityChongqing, Chongqing Municipality, ChinaNot Yet Recruiting
Chongqing Cancer HospitalChongqing, Chongqing Municipality, ChinaNot Yet Recruiting
The Southwest hospital of AMUChongqing, Chongqing Municipality, ChinaNot Yet Recruiting
Army Medical CenterChongqing, Chongqing Municipality, ChinaNot Yet Recruiting
Chongqing University Three Gorges HospitalChongqing, Chongqing Municipality, ChinaNot Yet Recruiting

+ 74 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06300177