Condition: Heart Failure With Reduced Ejection Fraction · Pulmonary Hypertension · Right Heart Failure Due to Left Heart Failure · Sponsor: Johns Hopkins University
Right ventricular (RV) failure is recognized to worsen patient outcomes in the setting of heart failure with reduced ejection fraction (HFrEF)-related pulmonary hypertension (PH), yet the investigators fall short in trying to identify and treat it. The current proposal will (1) determine the best clinical indicators of intrinsic RV myocyte contractile failure in humans with HFrEF-PH, (2) clarify underlying mechanisms, and (3) test novel treatments on RV myocytes. The long-term goal of this proposal will be to better identify and treat RV failure in humans suffering from HFrEF-PH.
This description comes directly from the study's public registry record.
Steven Hsu, MD · 410-502-0955 · steven.hsu@jhmi.edu
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| Johns Hopkins Hospital | Baltimore, Maryland, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06299436