Condition: Platelet Thrombus · Sponsor: Centro Cardiologico Monzino
Extracellular vesicles (EVs) play a key role in cell-to-cell communication. They are small vesicles that contain rich molecular cargo. Recently, they have been proposed as biomarkers for clinical diagnostics. EVs include three classes: small EVs (exosomes), large EVs (microparticles), and apoptotic bodies. Platelet-derived EVs (PEVs) are the most abundant class in human blood and can actively participate in numerous physiological and pathological processes. The information about the role of platelet exosomes in cardiovascular disease and the effect of antiplatelet agents on their release and content is very limited.
This description comes directly from the study's public registry record.
Silvia S Barbieri, PhD · 0258002021 · silvia.barbieri@ccfm.it
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| Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico | Milan, Italy | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06298682