Condition: Acute Ischemic Stroke · Sponsor: University of Milano Bicocca
The DOWN-SUITE study is multicenter, randomised, controlled, open-label clinical trial with blinded outcome assessment comparing collateral status in patients with acute ischemic stroke treated with an in-hospital application of head down tilt -10° to -15° (HDT15) versus usual positioning (0° to +30°) before endovascular mechanical thrombectomy. This study will involve adult patients who are eligible for mechanical thrombectomy and who have acute ischemic stroke due to left or right middle cerebral artery occlusion (M1 segment). The investigators hypothesise that HDT15, applied in acute ischemic stroke patients with a large vessel occlusion, will improve collateral circulation, prolong the survival of the ischemic penumbra and improve the clinical benefit from mechanical thrombectomy compared with standard of care (usual positioning 0° to +30°).
This description comes directly from the study's public registry record.
Simone Beretta, MD, PhD · +390392333568 · simone.beretta@unimib.it
BiCRO (academic CRO) · bicro@unimib.it
Always discuss trial participation with your own doctor first.
| Ospedale Civile SS. Nicola e Filippo Avezzano Pronto Soccorso | Avezzano, Italy | Not Yet Recruiting |
| Azienda Ospedaliero Universitaria Careggi | Florence, Italy | Not Yet Recruiting |
| Azienda Ospedaliera Policlinico Universitario "G. Martino" | Messina, Italy | Not Yet Recruiting |
| Fondazione IRCCS San Gerardo dei Tintori Monza | Monza, Italy | Recruiting |
| Azienda Ospedaliero Universitaria Policlinico Umberto I | Roma, Italy | Not Yet Recruiting |
| Ospedale Santa Maria della Misericordia | Udine, Italy | Not Yet Recruiting |
Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.
We email about this public record only. Unsubscribe anytime with one click. Never medical advice.
This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.
Source record: clinicaltrials.gov/study/NCT06297863