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Study identifier: NCT06297005 Synced from ClinicalTrials.gov · July 29, 2026
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The Impact of E-cigarettes During Pregnancy on Childhood Health Outcomes Study

Condition: Vaping · Pregnancy Related · Pediatric Respiratory Diseases  ·  Sponsor: University College Dublin

PhaseN/A
Planned participants1200
Who can joinFemale, 18 Years to 46 Years
Healthy volunteersYes

About this study

Tobacco smoking in pregnancy is now widely accepted as having adverse health outcomes for both the mother and fetus. Tobacco smoking in pregnancy is associated with increased incidence of miscarriage, stillbirth and preterm birth as well as low birthweight, respiratory infections, wheeze and asthma in childhood. E-cigarettes are a popular method for trying to quit smoking in Ireland and there has been an explosion in the use of e-cigarettes over the past ten years. However, there is currently insufficient evidence on their long-term safety and effectiveness as a smoking cessation tool. E-cigarettes contain varying combinations of compounds and flavours which are used differently in different e-cigarette types, with unknown long-term effects. Research has shown that pregnant women perceive e-cigarettes to be a healthier option when compared with tobacco smoking. But, there is very little known about the long-term health impact of exposure of unborn babies to e-cigarettes during pregnancy. The ECHO study will determine what the long-term health outcomes are in children born to mothers who use e-cigarettes during pregnancy. Specifically, we will focus on birth, nutritional, brain development and respiratory outcomes in children. To answer this research question, the ECHO study will recruit infants born to women who use e-cigarettes during pregnancy across three maternity hospitals and follow them up over 2 years. We will invite women at their booking visit to take part in this …

This description comes directly from the study's public registry record.

Talk to the study team

Des W Cox, MB BCh BAO  ·  +35314282638  ·  desmond.cox@ucd.ie

Carmen Regan, FRCOG  ·  cregan@coombe.ie

Always discuss trial participation with your own doctor first.

Locations (3)

Rotunda HospitalDublin, IrelandRecruiting
National Maternity Hospital, Holles StreetDublin, IrelandRecruiting
Coombe Womens HospitalDublin, IrelandRecruiting

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Source record: clinicaltrials.gov/study/NCT06297005