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Study identifier: NCT06296576 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Acceleration Time Assessment for Prediction of Critical Limb Ischemia

Condition: Critical Limb Ischemia  ·  Sponsor: Centre Hospitalier le Mans

PhaseN/A
Planned participants431
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Critical Limb Ischaemia (CLI), the final stage of arterial disease, is a therapeutic emergency whose prognosis depends largely on the time taken to diagnose it. The growing prevalence of this condition and the associated healthcare costs make it an important public health objective. Diagnostic criteria for Critical Limb Ischaemia differ between learned societies and countries. Its diagnosis is most frequently based on the combination of a clinical criterion (ischaemic decubitus pain and/or necrotic wounds, with a time to onset \> 2 weeks) and a haemodynamic criterion (ankle systolic pressure (ASP) \< 50mmHg or toe systolic pressure (TSP) \< 30 mmHg or transcutaneous oxygen pressure (TCPO2) \< 30 mmHg). Recent studies have highlighted the importance of pulsed Doppler flow analysis in quantifying arteriopathy of the lower limbs, both by systematically analysing flow modulation and by measuring the systolic rise time of distal arteries (dorsal artery of the foot and lateral plantar artery). The main aim of this study is therefore to validate a reliable and accessible diagnostic tool for screening patients suffering from CLI so that they can be referred to a reference centre as early as possible.

This description comes directly from the study's public registry record.

Talk to the study team

Christelle JADEAU  ·  +33244710781  ·  cjadeau@ch-lemans.fr

Jean-Eudes TRIHAN, MD  ·  02 41 49 62 49  ·  j.eudes.trihan@gmail.com

Always discuss trial participation with your own doctor first.

Locations (3)

Centre Hospitalier de CHOLETCholet, FranceRecruiting
Centre Hospitalier du MansLe Mans, FranceNot Yet Recruiting
CHU PoitiersPoitiers, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT06296576