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Study identifier: NCT06296186 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Massed Prolonged Exposure for PTSD in Substance Use Treatment

Condition: Stress Disorders, Post-Traumatic · Substance Use Disorders  ·  Sponsor: Veterans Medical Research Foundation

PhaseNA
Planned participants200
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to learn if receiving Prolonged Exposure Therapy for PTSD in massed format (multiple sessions weekly) is as effective as receiving it with sessions once per week among veterans with PTSD and substance use disorder in intensive outpatient substance use treatment. The main questions it aims to answer are: * Will the massed format help participants complete and benefit from Prolonged Exposure in terms of PTSD symptoms? * Will it help participants reduce substance use? Participants who are in intensive substance use treatment will be asked to complete Prolonged Exposure with either weekly sessions or multiple sessions per week.

This description comes directly from the study's public registry record.

Talk to the study team

Sonya Norman, PhD  ·  858-518-8266  ·  snorman@ucsd.edu

Kaitlyn Panza, PhD  ·  858-552-8585  ·  kaitlyn.panza@va.gov

Always discuss trial participation with your own doctor first.

Locations (4)

VA San Diego Healthcare SystemSan Diego, California, United StatesRecruiting
VA Tampa Healthcare SystemTampa, Florida, United StatesRecruiting
VA Atlanta Healthcare SystemAtlanta, Georgia, United StatesRecruiting
Hines VA Healthcare SystemChicago, Illinois, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06296186