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Study identifier: NCT06291987 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Ivosidenib and Ruxolitinib in Patients With Advanced Myeloproliferative Neoplasms (MPNs) That Have an IDH1 Gene Mutation

Condition: Myeloproliferative Neoplasms  ·  Sponsor: University of Chicago

PhasePhase 1
Planned participants18
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

The purpose of this research is to gather information on the safety and effectiveness determining maximum tolerated dose (MTD) of ruxolitinib in combination with ivosidenib in IDH1-mutated advanced-phase Ph-negative MPNs while evaluate the efficacy of ruxolitinib in combination with ivosidenib in IDH1-mutated advanced-phase Ph-negative MPNs.

This description comes directly from the study's public registry record.

Talk to the study team

Clinical Trials Intake  ·  1-855-702-8222  ·  cancerclinicaltrials@bsd.uchicago.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of Chicago Medicine Comprehensive Cancer CenterChicago, Illinois, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06291987