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Study identifier: NCT06290557 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

First-in-man Single-dose and Multiple Dose Study to Evaluate the Safety, Tolerability and Efficacy ofHY-133

Condition: Staphylococcus Aureus  ·  Sponsor: University Hospital Tuebingen

PhasePhase 1
Planned participants52
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

In this clinical trial we will test a new approach for decolonization of S. aureus. As innovative product HY-133 a recombinant chimeric bacteriophage endolysin will be sprayed in both nostrils of healthy subjects once or five times in one day. To avoid possible bias the subjects will be randomized 3:2 verum vs placebo, moreover the subject as well as the investigator will be blinded to the group assigned.

This description comes directly from the study's public registry record.

Talk to the study team

Sebastian Volc, PD  ·  07071 2926745  ·  studienzentrum.immundermatologie@med.uni-tuebingen.de

Always discuss trial participation with your own doctor first.

Locations (2)

Department of Dermatology, University Hospital TuebingenTübingen, GermanyRecruiting
Department of DermatologyTübingen, GermanyRecruiting

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Source record: clinicaltrials.gov/study/NCT06290557