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Study identifier: NCT06287528 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study of 19-28z/IL-18 in People With Acute Lymphoblastic Leukemia (ALL)

Condition: Philadelphia-Negative ALL · Philadelphia-Positive ALL · Relapsed ALL, Adult  ·  Sponsor: Memorial Sloan Kettering Cancer Center

PhasePhase 1
Planned participants18
Who can joinAll sexes, 17 Years to no upper limit
Healthy volunteersNo

About this study

Participants will have a sample of their white blood cells, called T cells, collected using a procedure called leukapheresis. The collected T cells will be sent to a laboratory to be changed (modified) to become 19-28z/IL-18, the CAR T-cell therapy that participants will receive during the study. Making the participants' study therapy will take about 2-4 weeks.

This description comes directly from the study's public registry record.

Talk to the study team

Jae Park, MD  ·  646-608-3743  ·  parkj6@mskcc.org

Mark Geyer, MD  ·  646-608-3745  ·  geyerm@mskcc.org

Always discuss trial participation with your own doctor first.

Locations (7)

Memorial Sloan Kettering at Basking Ridge (Limited Protocol Activities)Basking Ridge, New Jersey, United StatesRecruiting
Memorial Sloan Kettering Monmouth (Limited Protocol Activities)Middletown, New Jersey, United StatesRecruiting
Memorial Sloan Kettering Bergen (Limited Protocol Activities)Montvale, New Jersey, United StatesRecruiting
Memorial Sloan Kettering Cancer Suffolk-Commack (Limited Protocol Activities)Commack, New York, United StatesRecruiting
Memorial Sloan Kettering Westchester (Limited Protocol Activities)Harrison, New York, United StatesRecruiting
Memorial Sloan Kettering Cancer Center (All Protocol Activities)New York, New York, United StatesRecruiting
Memorial Sloan Kettering Nassau (Limited Protocol Activities)Uniondale, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06287528