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Study identifier: NCT06287034 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

The Role of the Free/Pedunculated Flap in Total Laryngectomy After (Chemo-)Radiotherapy Failure for Laryngeal Carcinoma: Impact on the Risk of Pharyngocutaneous Fistula (PCF)

Condition: Larynx Carcinoma  ·  Sponsor: Regina Elena Cancer Institute

PhaseN/A
Planned participants102
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Multicenter, prospective, randomized study aimed at evaluating the difference in risk of PCF after salvage laryngectomy in two groups of patients: one cohort treated with Total Laryngectomy (LT) with primary suture, a second group treated with LT and reinforcement by flap positioning with onlay technique (PMM, ALT)

This description comes directly from the study's public registry record.

Talk to the study team

Raul Pellini, Doctor  ·  06-52664484  ·  raul.pellini@ifo.it

Always discuss trial participation with your own doctor first.

Locations (1)

"Regina Elena" National Cancer InstituteRome, Rome, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT06287034