← Eichor
Study identifier: NCT06284590 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Study of the Efficacy of Intratumoral L19IL2 or L19TNF or L19IL2/L19TNF, in Combination with Pembrolizumab, in Unresectable Melanoma Patients

Condition: Melanoma Stage III · Melanoma Stage IV  ·  Sponsor: Philogen S.p.A.

PhasePhase 2
Planned participants162
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The trial aims to evaluate the efficacy of single agent L19IL2, single agent L19TNF, and combination L19IL2+L19TNF given concurrently with anti-PD1 therapy compared to historical control of anti-PD-1 re-challenge alone for anti-PD1 refractory unresectable stage III-IV melanoma.

This description comes directly from the study's public registry record.

Talk to the study team

Giuliano Elia, PhD  ·  +39 057717816  ·  regulatory@philogen.com

Marco Taras  ·  +39 057717816  ·  regulatory@philogen.com

Always discuss trial participation with your own doctor first.

Locations (1)

Memorial Sloan Kettering Cancer CenterNew York, New York, United StatesRecruiting

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT06284590