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Study identifier: NCT06284434 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Liposomal Bupivacaine Use in Alveolar Bone Graft Patients

Condition: Cleft Lip and Palate  ·  Sponsor: Kerry O'Rourke

PhasePhase 3
Planned participants60
Who can joinAll sexes, 6 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to learn if a pain medication called liposomal bupivacaine (brand name EXPAREL®) with epinephrine will provide better pain control, increased activity, and reduced use of opioids compared with the standard treatment for patients age 6 years and older with cleft lip and palate who have had an alveolar bone graft surgery. Investigators will look at: * pain scores at hip and jaw sites * opioid use in amount and frequency * scores on activity questionnaires Researchers will compare the results of these items with those of patients who had the standard treatment of bupivacaine with epinephrine.

This description comes directly from the study's public registry record.

Talk to the study team

Chad A. Purnell, MD  ·  (724)-433-1645  ·  cpurnell@shrinenet.org

Benjamin M. Smith, MS  ·  (773) 385-5865  ·  BenjaminM.Smith@shrinenet.org

Always discuss trial participation with your own doctor first.

Locations (1)

Shriners Children's ChicagoChicago, Illinois, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06284434