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Study identifier: NCT06283940 Synced from ClinicalTrials.gov · July 29, 2026
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Exercise-based Cardiac Rehabilitation in Patients With Aortic Stenosis After Transcatheter Aortic Valve Implantation

Condition: Aortic Valve Stenosis  ·  Sponsor: Vastra Gotaland Region

PhaseNA
Planned participants135
Who can joinAll sexes, 65 Years to no upper limit
Healthy volunteersNo

About this study

Aortic valve stenosis (AS) is the most common valve disease among older individuals. In symptomatic AS, mortality is high, and the only treatment that improves prognosis and survival is transcatheter aortic valve implantation (TAVI). TAVI is a growing treatment in Sweden, allowing previously inoperable older patients with AS, who are often frail and have comorbidities, to receive intervention. This results in the need for postoperative cardiac rehabilitation for patients treated with TAVI. Previous systematic reviews and meta-analyses examining the effect of physiotherapist-led exercise-based cardiac rehabilitation (PT-X) after TAVI have shown that participation in PT-X can improve physical fitness (the highest measured oxygen uptake (VO2peak)), walking distance, walking speed, and health-related quality of life (HR-QoL). However, the included studies are limited, and there is selection bias, resulting in low evidence. Therefore, access to PT-X is currently almost non-existent in Sweden. As more patients undergo TAVI, it is crucial to investigate whether PT-X after TAVI can further improve physical fitness, HR-QoL, and reduce hospital admissions in older individuals with AS. Objective: Primary, to investigate whether participation in PT-X after TAVI can impact physical fitness, physical activity level, and health-related quality of life. Secondary, to study the prevalence of frailty and the number of hospital admissions during the first postoperative year after TAVI. Expect…

This description comes directly from the study's public registry record.

Talk to the study team

Maria C Borland, Phd RPT  ·  +46700816894  ·  maria.borland@vgregion.se

Always discuss trial participation with your own doctor first.

Locations (1)

SV Hospital group Alingsås hospitalAlingsås, SwedenRecruiting

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Source record: clinicaltrials.gov/study/NCT06283940