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Study identifier: NCT06282406 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Pupil-Indexed Noninvasive Neuromodulation

Condition: Paresis  ·  Sponsor: VA Office of Research and Development

PhaseNA
Planned participants110
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersYes

About this study

Vagus nerve stimulation (VNS) is thought to activate neural pathways that release chemicals which promote plasticity and learning. Previous work has shown that the auricular branch of the vagus nerve innervates landmarks on the external ear. Work from the PI's laboratory has shown that electrical current applied to the external ear modulates physiological indexes of brain states implicated in the therapeutic effects of VNS. The broad objective of this project is to better understand physiological mechanisms modulated by auricular stimulation to support possible therapeutic effects in the form of motor learning.

This description comes directly from the study's public registry record.

Talk to the study team

Michael A Urbin, PhD  ·  (412) 688-6000  ·  Michael.Urbin@va.gov

Always discuss trial participation with your own doctor first.

Locations (1)

VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PAPittsburgh, Pennsylvania, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06282406