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Study identifier: NCT06281756 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Cognitive Behavioral Therapy and Trazodone Effects on Sleep and Blood Pressure in Insomnia

Condition: Insomnia · Insomnia Chronic · Insomnia, Primary  ·  Sponsor: Milton S. Hershey Medical Center

PhaseEARLY_Phase 1
Planned participants600
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Individuals who have insomnia with short sleep duration (ISS) differ from individuals who have insomnia with normal sleep duration (INS) in terms of health risks (i.e., hypertension) and treatment response. This study will examine whether patients with ISS and INS demonstrate a differential response to two common insomnia treatments. One is behavioral, Cognitive Behavioral Therapy for Insomnia (CBT-I). The other is a widely prescribed, non-habit-forming medication, trazodone used at a low dose. The investigators' findings could lead to evidence-based treatment guidelines that help clinicians more effectively match treatments to insomnia patients and reduce associated health problems.

This description comes directly from the study's public registry record.

Talk to the study team

Carrie Criley  ·  717-531-4123  ·  ccriley@pennstatehealth.psu.edu

Always discuss trial participation with your own doctor first.

Locations (4)

National Jewish HealthDenver, Colorado, United StatesRecruiting
Penn State UniversityHershey, Pennsylvania, United StatesRecruiting
University of PittsburghPittsburgh, Pennsylvania, United StatesRecruiting
Université LavalQuébec, Quebec, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT06281756