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Study identifier: NCT06281067 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Reassessment of myocardIAL Bridge TOwards PeRsOnalized Medicine

Condition: Myocardial Bridge  ·  Sponsor: Azienda Ospedaliero Universitaria Maggiore della Carita

PhaseNA
Planned participants500
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

The "RIALTO-PRO" study aims to optimize the diagnostic and therapeutic algorithm for myocardial bridge (MB) patients, testing the diagnostic value of a full invasive diagnostic procedure, and, consequently, the prognostic value of a tailored approach. the study objective is to determine the diagnostic and prognostic value of a full-physiology approach strategy versus a standard approach strategy in patients with a MB. The "RIALTO PRO" study is a randomized, multicentre, prospective, open-label, superiority trial comparing a personalised versus standard management in patients with MB. Consenting and eligible patients will be randomised 1:1 to either a "full-physiology approach", consisting of a comprehensive diagnostic algorithm aimed at unmasking the main pathophysiological mechanism of myocardial ischemia and consequently a tailored treatment, or a "standard approach", consisting of angiographic evaluation of the tunnelled segment.

This description comes directly from the study's public registry record.

Talk to the study team

Domenico D'Amario, Prof  ·  0039 0321 3733141  ·  domenico.damario@uniupo.it

Always discuss trial participation with your own doctor first.

Locations (34)

Ospedale Generale Regionale F. MiulliAcquaviva delle Fonti, ItalyNot Yet Recruiting
Azienda Ospedaliera Nazionale Santi Antonio e Biagio e Cesare ArrigoAlessandria, ItalyNot Yet Recruiting
Ospedale San DonatoArezzo, ItalyNot Yet Recruiting
ASST Papa Giovanni XXIIIBergamo, ItalyNot Yet Recruiting
Ospedale degli Infermi di BiellaBiella, ItalyNot Yet Recruiting
Policlinico S. Orsola IRCCS Azienda Ospedaliero UniversitariaBologna, ItalyNot Yet Recruiting
Azienda Ospedaliera di Rilievo Nazionale Sant'Anna e San SebastianoCaserta, ItalyNot Yet Recruiting
Villa Maria Cecilia HospitalCotignola, ItalyNot Yet Recruiting
Azienda Ospedaliero Universitaria di FerraraFerrara, ItalyNot Yet Recruiting
Azienda Ospedaliero Universitaria CareggiFlorence, ItalyNot Yet Recruiting
Azienda Ospedaliera Universitaria Policlinico San MartinoGenova, ItalyNot Yet Recruiting
Ospedale Della MisericordiaGrosseto, ItalyNot Yet Recruiting

+ 22 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06281067