Condition: Cardiovascular Diseases · Cardiovascular Complication · Perioperative Complication · Sponsor: Cantonal Hospital of St. Gallen
Perioperative myocardial injury and major adverse cardiovascular events (MACE) are common causes of morbidity and mortality in patients at increased cardiovascular risk undergoing non-cardiac surgery. However, research in recent years has yielded limited preventive and therapeutic measures for myocardial injury/MACE. Recent studies in patients with chronic and acute coronary artery disease have shown that colchicine administration can reduce the risk of cardiovascular events. These encouraging results in non-surgical patients ask for a similar investigation in patients undergoing major non-cardiac surgery. The aim of the proposed study is to investigate the effects of perioperative colchicine administration on the incidence of myocardial injury/MACE.
This description comes directly from the study's public registry record.
Timur Yurttas, MD · 0041 714949158 · timur.yurttas@kssg.ch
Miodrag Filipovic, Prof. MD. · 0041714941111 · miodrag.filipovic@kssg.ch
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| Cantonal Hospital St. Gallen | Sankt Gallen, Canton of St. Gallen, Switzerland | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06279000