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Study identifier: NCT06277037 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Long-Term Follow-up Study for Subjects With CHB Previously Treated With Imdusiran (AB729)

Condition: Long Term Follow-up  ·  Sponsor: Arbutus Biopharma Corporation

PhaseN/A
Planned participants50
Who can joinAll sexes, 20 Years to 70 Years
Healthy volunteersNo

About this study

This is a long term follow-up study for chronic hepatitis B (CHB) subjects who have received imdusiran treatment in a prior clinical trial, stopped NA therapy during that trial, and remain off therapy. Subjects may enroll after completing the end of study visit (baseline visit within 12 weeks ± 1 week from the end of study \[EOS\] visit) from their imdusiran clinical trial (the "parent study"). No interventions will be performed in this study other than blood sample collections, review of current medications, and reporting of any adverse events related to study procedures or NA therapy if restarted. Study participation will be for approximately 2 years (to complete a total of at least 3 years of follow-up while off NA therapy, inclusive of parent study participation).

This description comes directly from the study's public registry record.

Talk to the study team

Michael Child  ·  267-332-6213  ·  mchild@arbutusbio.com

Always discuss trial participation with your own doctor first.

Locations (18)

Research and Education Inc.San Diego, California, United StatesRecruiting
University of Miami Miller School of MedicineMiami, Florida, United StatesNot Yet Recruiting
Infectious Disease CareHillsborough, New Jersey, United StatesRecruiting
The Alfred HospitalMelbourne, Victoria, AustraliaRecruiting
Fiona Stanley HospitalMurdoch, AustraliaNot Yet Recruiting
Prince of Wales HospitalShatin, New Territories, Hong KongRecruiting
Queen Mary HospitalHong Kong, Hong KongRecruiting
Arensia Exploratory Medicine MoldovaChisinau, MoldovaRecruiting
Asan Medial CenterSeoul, South KoreaNot Yet Recruiting
Changhua Christian HospitalChanghua, TaiwanRecruiting
Chia-Yi Christian HospitalChiayi City, TaiwanRecruiting
Kaohsiung Medical University Chung-Ho Memorial HospitalKaohsiung City, TaiwanRecruiting

+ 6 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06277037