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Study identifier: NCT06275386 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Drug-Coated Balloon in Native Chronic Total Occlusion Percutaneous Coronary Intervention

Condition: Coronary Artery Disease · Total Occlusion of Coronary Artery  ·  Sponsor: National Institute of Cardiology, Warsaw, Poland

PhaseNA
Planned participants30
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The IMAGINATION trial is an investigator-initiated, prospective, single-center study of symptomatic patients with a native chronic total occlusion (CTO) undergoing intravascular ultrasound (IVUS)-guided percutaneous coronary intervention (PCI) with a drug-coated balloon (DCB). Post-PCI IVUS and fractional flow reserve (FFR) at baseline and at 6-months follow-up will be performed. In addition, patients included in the coronary computed tomography angiography (CCTA) substudy will undergo CCTA at 12-months follow-up. The aim of this study is to evaluate the efficacy and safety of DCB-only approach in native coronary CTO.

This description comes directly from the study's public registry record.

Talk to the study team

Maksymilian Opolski  ·  0048(22)3434127  ·  mopolski@ikard.pl

Always discuss trial participation with your own doctor first.

Locations (1)

National Institute of CardiologyWarsaw, Masovian Voivodeship, PolandRecruiting

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Source record: clinicaltrials.gov/study/NCT06275386