Condition: Gastric Cancer · H Pylori Infection · H Pylori Eradication · Sponsor: University of Latvia
Gastric cancer remains a major challenge to public health on a global scale. H. pylori related cancer burden contributes to the largest proportion of cancer cases attributable to infections in Europe. Considering its absolute burden and persisting disparities, in addition to the substantial prevalence of H. pylori infection worldwide that is treatable, gastric cancer is a logical target for urgent action for prevention. Population-based H. pylori test-and-treat has therefore been proposed as a strategy for gastric cancer prevention. To fill the gaps in knowledge about gastric cancer prevention through H. pylori screening and eradication in younger adults, a study of a population-based H. pylori test-and-treat strategy in Ireland, Croatia, Latvia, Poland, Romania and Slovenia. Main goals of this study are to assess future program processes, feasibility, acceptability and effectiveness. In total of 6,800 adults aged 30-34 will be tested for H. pylori infection. They will be randomly selected to represent the chosen population and invited to participate in the study based on informed consent. Confirmed infections will be treated by available combined therapy in line with treatment guidelines and the success of eradication will be retested during a control check-up. Patients who will provide their consent to participate will undertake an interview about the risk factors in early childhood and their habits regarding alcohol consumption and use of tobacco. Compliance to testing a…
This description comes directly from the study's public registry record.
Principal Investigator of the Study - Bojan Tepeš (National Institute of Public Health, Slovenia), Prof., MD · 0038641325916 · bojan.tepes@siol.net
Tatjana Kofol Bric (National Institute of Public Health, Slovenia), MD · 0038612441484 · Tatjana.Kofol@nijz.si
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| University Hospital Centre Zagreb | Zagreb, City of Zagreb, Croatia | Recruiting |
| Clinical Hospital Center Rijeka | Rijeka, Croatia | Recruiting |
| Beacon Hospital | Dublin, Ireland | Recruiting |
| Clinical and Preventive Medicine of the University of Latvia | Riga, Latvia | Not Yet Recruiting |
| Wroclaw Medical University | Wroclaw, Poland | Recruiting |
| Iuliu Hatieganu University of Medicine and Pharmacy | Cluj-Napoca, Cluj, Romania | Recruiting |
| National Institute of Public Health, Slovenia | Ljubljana, Slovenia | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06275204