Condition: Ovarian Cancer Stage III · Ovarian Cancer Stage IV · Sponsor: University of Udine
A detailed understanding of molecular mechanism of cancer genesis is fundamental to develop innovative and personalized therapies. The new frontier in biomedical research is represented by organoids, a three-dimensional cell culture system obtained from a tissue fragment that accurately reproduces the essential properties of the original tissue in vitro, which could provide a valuable model for explanation of ovarian cancers pathogenesis and will allow to predict the response to a specific therapy. With this research project, we expect to generate ovarian cancer organoids to characterize in vitro interactions and molecular pathway among tumor cells, immune cells, and resident microbiota (intratumoral bacteria and/or microbial-derived molecules).
This description comes directly from the study's public registry record.
Giuseppe Vizzielli, Prof. · 3403990822 · giuseppe.vizzielli@uniud.it
Arcieri Martina, Dott.ssa · 3478114704 · martina.arcieri@asufc.sanita.fvg.it
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| Università degli Studi di Udine | Udine, UD, Italy | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06272240