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Study identifier: NCT06270407 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

The Effect of Local Application of Tranexamic Acid Versus Placebo on Postoperative Complications in Plastic Surgery

Condition: Surgical Complication  ·  Sponsor: St. Olavs Hospital

PhasePhase 4
Planned participants3000
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Study objective: This is a study to investigate whether applying the drug tranexamic acid (TXA) onto a surgical wound surface may affect the incidence of surgical complications such as re-bleeding needing intervention, wound complications such as infection, wound rupture or seroma, or if it may increase the risk of blood clots. Eligible patients: Patients undergoing plastic surgical procedures with wounds that would normally receive application of TXA to reduce bleeding after surgery. Study intervention: Participants will receive a single local application of study drug onto their wound surfaces at the end of surgery. Study drug will be identical looking ampoules which contain either TXA or placebo (saline). Neither participants nor study personnel will know the contents of the ampoules.

This description comes directly from the study's public registry record.

Talk to the study team

Kjersti Ausen, MD PhD  ·  +4792249693  ·  kjerstiausen@gmail.com

Olav Spigset, MD PhD  ·  +47 936 64 337  ·  olav.spigset@legemidler.no

Always discuss trial participation with your own doctor first.

Locations (1)

St Olav's University HospitalTrondheim, NorwayRecruiting

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Source record: clinicaltrials.gov/study/NCT06270407