Condition: Infective Endocarditis · Sponsor: Nantes University Hospital
1\. Infective Endocarditis (IE) is a rare and serious disease with high morbidity and mortality; 2. Streptoccoci of oral origin are the second more frequent microorganisms responsible for IE; 3. Oral Infectious Foci (OIF) are underdetected using the current recommended clinical examination/Orthopantomogram (OPT) approach; 4. Cone Beam Computed Tomography (CBCT) has a better sensitivity and sensibility to detect OIF than OPT; 5. To date, no study has been performed to assess the potential benefit of a clinical examination/CBCT approach on the oral health status in IE patients. Thus, conducting a randomized controlled trial is highly desirable to assess the potential impact of a clinical examination/CBCT approach on the oral health status of patients hospitalized for IE and potentially to reduce IE new episodes.
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Contact details are listed per location below or on the registry record.
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| CHU Bordeaux - Site Pellegrin | Bordeaux, France | Recruiting |
| CHU Clermont-Ferrand | Clermont-Ferrand, France | Recruiting |
| CHU Grenoble | Grenoble, France | Recruiting |
| HCL | Lyon, France | Recruiting |
| APHM | Marseille, France | Recruiting |
| CHRU Nancy | Nancy, France | Recruiting |
| CHU Nantes | Nantes, France | Recruiting |
| AP-HP - Site Bretonneau | Paris, France | Recruiting |
| CHU Toulouse | Toulouse, France | Recruiting |
| CHRU Tours | Tours, France | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06269679