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Study identifier: NCT06268431 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Oxytocin Rest to Reduce Cesarean Delivery

Condition: Prolonged Labor · Failed Induction · Labor Dystocia  ·  Sponsor: Christiana Care Health Services

PhaseNA
Planned participants350
Who can joinFemale, 18 Years to 55 Years
Healthy volunteersNo

About this study

Prolonged labor is usually managed with continuous oxytocin infusion. "Oxytocin rest" has been proposed as a strategy to resolve protracted labor in patients who have received continuous oxytocin without progress. This strategy involves discontinuing oxytocin then restarting infusion after a period of time, under the theory that washout of the oxytocin receptor will strengthen uterine contractions to improve labor progress. "Oxytocin rest" is performed on labor and delivery units across the United States. Yet, there is no randomized or prospective data to support the practice. The purpose of this study is to assess whether oxytocin rest of 60 minutes in patients with prolonged labor reduces risk for cesarean delivery.

This description comes directly from the study's public registry record.

Talk to the study team

Teresa C Logue  ·  (302)-733-6563  ·  teresa.logue@christianacare.org

Always discuss trial participation with your own doctor first.

Locations (1)

ChristianaCare Health SystemNewark, Delaware, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06268431