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Study identifier: NCT06266715 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Improvement of Depression With Use of ATP

Condition: Depression  ·  Sponsor: Nanfang Hospital, Southern Medical University

PhaseNA
Planned participants120
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

This clinical study is a randomized, double-blind, placebo-controlled trial with an intervention period of 4 weeks. Participants will be patients with moderate to severe depression who meet the inclusion criteria during the screening period. After recruitment written informed consent form will be signed and the baseline evaluation will be done then the treatment period follows. The subjects will be randomly assigned to a control group (escitalopram plus normal saline(NA)) and an ATP group (escitalopram plus adenosine disodium triphosphate(ATP)) in a 1:1 ratio for treatment, with a total number of 120 recruited patients. Assessment will be carried out as an analysis of changes in Hamilton Depression Scale(HAMD-24), cognitive function test, brain functional network, inflammatory markers, and other indicators in the first, second, and fourth week of intervention which will evaluate the effectiveness of ATP in improving moderate to severe depression preliminarily.

This description comes directly from the study's public registry record.

Talk to the study team

Bin Zhang, PhD  ·  86-020-62786731  ·  zhang73bin@hotmail.com

Qianqian Xin, MMed  ·  86-020-62786731

Always discuss trial participation with your own doctor first.

Locations (1)

Nanfang Hospital, Southern Medical UniversityGuangzhou, Guangdong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06266715