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Study identifier: NCT06265558 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Prevention of Postoperative Complications by Negative Pressure Therapy After Complex Breast Cancer Surgery

Condition: Breast Cancer  ·  Sponsor: Institut du Cancer de Montpellier - Val d'Aurelle

PhaseNA
Planned participants254
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

There is little scientific data concerning the use of negative pressure therapy after immediate breast reconstruction. That strategy of treatment-reconstruction has expanded increasingly since the last years. The current literature reports only 3 studies on the use of preventive negative pressure therapy in oncologic breast surgery. Moreover, all three are retrospective, case-control studies with serious limitations. The largest published series reports a reduction in the overall complication rate from 15.9% to 8.5%, and a significant reduction in several criteria: infection, scar dehiscence and necrosis. However, the study presents significant biases, with non-comparable populations in terms of comorbidities, surgical procedure performed, inclusion periods (and therefore experience in performing oncological surgery). There was also a high probability of under-assessment or postponement of post-operative complications, which is typical of published retrospective surgical studies. The published results therefore strongly encourage further investigation of negative pressure therapy in oncological breast surgery.

This description comes directly from the study's public registry record.

Talk to the study team

Mathias NERON, MD  ·  467614813  ·  mathias.neron@icm.unicancer.fr

Always discuss trial participation with your own doctor first.

Locations (7)

Centre Georges-François LeclercDijon, Côte d'Or, FranceNot Yet Recruiting
Centre Hospitalier de NîmesNîmes, GARD, FranceRecruiting
Institut BergoniéBordeaux, Gironde, FranceNot Yet Recruiting
Centre Hospitalier de MontpellierMontpellier, Hérault, FranceRecruiting
Institut régional du Cancer de MontpellierMontpellier, Hérault, FranceRecruiting
Institut de Cancérologie de l'OuestAngers, Maine Et Loire, FranceRecruiting
Centre Léon BérardLyon, Rhône, FranceNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT06265558