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Study identifier: NCT06263868 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

First Observatory of Precocious Puberty.

Condition: Puberty, Precocious  ·  Sponsor: Hospices Civils de Lyon

PhaseN/A
Planned participants3360
Who can joinAll sexes, N/A to 11 Years
Healthy volunteersYes

About this study

The age of puberty has fluctuated throughout history. Recent data shows an increase in the age of onset of puberty signs, in the United States but also in Europe. A recent Public Health France study published in 2018 reports an increase in the incidence of precocious puberty with geographical heterogeneity. The consequences of these appearances include the early onset of menarche, short adult height and the psychological impact. Due to a lack of studies and additional data, the reasons for this development are difficult to understand. Among current hypotheses, the entanglement with the evolution of our environment is at the forefront: the action of environmental endocrine disruptors and nutritional factors could play a role in the process of early appearance of pubertal signs. The establishment of a national observatory for early and advanced puberty in collaboration with pediatric endocrinologists (on the front line) would allow a reliable and precise field approach, capable of supplementing epidemiological data, which are currently insufficient. The investigators hypothesize that the establishment of an observatory of pubertal advances (early puberty and advanced puberty) in private medicine is possible, with inclusion of at least 75% of eligible patients, and collection of at least 80% of data.

This description comes directly from the study's public registry record.

Talk to the study team

Emillie Doye, MD  ·  0472118890  ·  emilie.doye@chu-lyon.fr

Tiphanie GINHOUX  ·  0427857723  ·  Tiphanie.ginhoux01@chu-lyon.fr

Always discuss trial participation with your own doctor first.

Locations (25)

Clinique du Val d'OuestÉcully, Auvergne-Rhône-Alpes, FranceRecruiting
Clinique du Val d'OuestÉcully, Auvergne-Rhône-Alpes, FranceRecruiting
Clinique du Val d'OuestÉcully, Auvergne-Rhône-Alpes, FranceRecruiting
Pediatric practiceLyon, Auvergne-Rhône-Alpes, FranceRecruiting
Pediatric practiceRennes, Brittany Region, FranceRecruiting
Pediatric practiceChambray-lès-Tours, Centre-Val de Loire, FranceRecruiting
Pediatric practiceEssey-lès-Nancy, Grand Est, FranceRecruiting
Pediatric practiceLevallois-Perret, Hauts-de-Seine, FranceActive Not Recruiting
Pediatric practiceFondettes, Indre-et-Loire, FranceRecruiting
Polyclinique Bordeaux rive droiteLormont, New Aquitaine, FranceActive Not Recruiting
Pediatric practicePau, New Aquitaine, FranceRecruiting
Pediatric PracticePessac, New Aquitaine, FranceRecruiting

+ 13 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06263868