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Study identifier: NCT06263530 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Prognostic Significance of ctDNA in HL

Condition: Prognostic Cancer Model  ·  Sponsor: Interni hematologicka klinika FNKV

PhaseN/A
Planned participants500
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Specific somatic mutations using ctDNA will be analyzed in predefined subgroups of cHL (e.g., age \<60 and ≥ 60 years, EBV). These mutations will be correlated with response to the treatment in the first line, in the relapse, during brentuximab vedotin and/or nivolumab treatment. Circulating tumor DNA will be correlated with the extent of tumor mass and chemo/radiotherapy.

This description comes directly from the study's public registry record.

Talk to the study team

Heidi Mocikova, M.D., Ph.D.  ·  +420267163554  ·  heidi.mocikova@fnkv.cz

Ondrej Havranek, assoc. prof.  ·  +420325873029  ·  ondrej.havranek@lf1.cuni.cz

Always discuss trial participation with your own doctor first.

Locations (5)

University Hospital Hradec KraloveHradec Králové, CzechiaRecruiting
University Hospital OlomoucOlomouc, CzechiaRecruiting
University Hospital Kralovske VinohradyPrague, CzechiaRecruiting
Charles UniversityPrague, CzechiaActive Not Recruiting
General University HospitalPrague, CzechiaRecruiting

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Source record: clinicaltrials.gov/study/NCT06263530