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Study identifier: NCT06263387 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Results From a French Temporary Utilization Authorization of First-line Acute Myeloid Leukemia (AML) Patients Ineligible for Intensive Chemotherapy (IC), Treated With Venetoclax Azacitidine

Condition: AML, Adult  ·  Sponsor: French Innovative Leukemia Organisation

PhaseN/A
Planned participants230
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Following the results of the phase 1b and the phase 3 studies, Venetoclax/Azacitidine (VEN/AZA) was available in France for newly diagnosed AML patients ineligible-IC patients through the early access program the so-called ATU program. Venetoclax (VEN) has been available in France through the ATU since Feb 2021 and through the current post-ATU schema from the point of marketing authorization approval and up to the pending publication of reimbursement and price. Between February 15, 2021, and June 30, 2021, 285 requests for ATU were made to the pharmaceutical company (Abbvie) and led to the initiation of treatment of more than 230 patients. At the end of ATU period, all these 230 ATU patients continued to be treated by VEN/AZA as part of the current post-ATU period. Healthcare professionals and health care decision makers need real world data to better understand the benefit/risk profile of treatment. Early access to treatment in France is close to real-life setting condition.

This description comes directly from the study's public registry record.

Talk to the study team

Ariane MINEUR  ·  +33 (0)5 57 62 31 08  ·  ariane.mineur@chu-bordeaux.fr

Always discuss trial participation with your own doctor first.

Locations (42)

Amiens CHUAmiens, FranceNot Yet Recruiting
Angers CHUAngers, FranceNot Yet Recruiting
Avignon CHAvignon, FranceNot Yet Recruiting
Bayonne CHBayonne, FranceNot Yet Recruiting
Besançon CHUBesançon, FranceRecruiting
Brest CHUBrest, FranceNot Yet Recruiting
Caen CHUCaen, FranceNot Yet Recruiting
CERGY PONTOISE - CH René DubosCergy-Pontoise, FranceNot Yet Recruiting
Hôpital d'Instruction des Armées PERCYClamart, FranceNot Yet Recruiting
CHU EstaingClermont-Ferrand, FranceNot Yet Recruiting
Corbeil-Essonnes - Ch Sud FrancilienCorbeil-Essonnes, FranceNot Yet Recruiting
Créteil CHU HENRI MONDORCréteil, FranceNot Yet Recruiting

+ 30 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06263387