Condition: Dexamethasone During Pregnancy · Sponsor: Assistance Publique - Hôpitaux de Paris
This study will analyze obstetric, endocrine and metabolic follow-up data in women treated with DEX. It will reveal the prevalence and importance of weight gain, insomnia, edema, stretch marks, arterial hypertension and gestational diabetes, describe pregnancy outcome, and analyze the corticotropic axis during and up to 3 months after pregnancy, with the aim of improving the management of these women and preventing comorbidities. A few studies suggest problems in women treated with DEX during pregnancy. However, all these studies are retrospective, based on self-questionnaires, and have not evaluated all pregnancy outcomes. Moreover, it would appear that a third of women treated with DEX no longer wish to resume the treatment (8). Compliance with treatment is strongly linked to its efficacy. It is therefore important to start investigating the pregnancy outcomes of women treated with DEX. This project is relevant because it has the potential to improve current clinical practice and recommendations related to this treatment, and thus have a direct impact on future patient care. The results of this study will guide us in the management of women presenting an indication for prenatal DEX treatment, and will help to inform the Order of November 15, 2022.
This description comes directly from the study's public registry record.
Anne BACHELOT, Pr · 01 42 16 02 46 · anne.bachelot@aphp.fr
Imene HADDADOU, CP · 01.42.16.24.98 · imene.haddadou@aphp.fr
Always discuss trial participation with your own doctor first.
| Hopital Haut Leveque - Endocrinologie | Bordeaux, France | Recruiting |
| Endocrinologie - Hospices civils de Lyon | Bron, France | Recruiting |
| Hospices civils de Lyon Biochimie et Biologie moléculaire UM Pathologies endocriniennes | Bron, France | Recruiting |
| Hospices civils de Lyon Laboratoire de Biologie Médicale Multi Sites | Bron, France | Recruiting |
| Hospices civils de Lyon Service de médecine de la reproduction | Bron, France | Recruiting |
| Endocrinologie - CHU Grenoble - Hôpital Michallon | Grenoble, France | Recruiting |
| Endocrinologie et médecine de la reproduction - Hôpital Bicêtre APHP | Le Kremlin-Bicêtre, France | Recruiting |
| Endocrinologie pédiatrique - Hôpital Bicêtre APHP | Le Kremlin-Bicêtre, France | Recruiting |
| Hopital Bicêtre | Le Kremlin-Bicêtre, France | Recruiting |
| CHRU Lille - Hôpital Claude Huriez Endocrinologie, diabétologie et métabolisme | Lille, France | Recruiting |
| Biologie et médecine de la reproduction, centre d'Assistance Médicale à la Procréation - CHU Nantes - Hôpital Mère et Enfant | Nantes, France | Recruiting |
| Hospital Saint-Antoine, Endocrinology service | Paris, France | Recruiting |
+ 5 more locations — full list on the registry record.
Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.
We email about this public record only. Unsubscribe anytime with one click. Never medical advice.
This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.
Source record: clinicaltrials.gov/study/NCT06259994