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Study identifier: NCT06258382 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Fontan Circulation and Reproductive Health in a National Swedish Cohort

Condition: Fontan Circulation  ·  Sponsor: Caroline Lilliecreutz

PhaseN/A
Planned participants600
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

In the Swedish registry for congenital heart defects, SWEDCON, over 230 patients with single-ventricle circulation are registered in the adult section. Congenital heart defects affect career choices, family planning, and leisure activities. Questions regarding heredity and pregnancy are common. The impact of Fontan circulation on reproductive health and fertility needs to be illuminated, and additional studies are required from both medical and psychosocial perspectives.Cognitive impairment is common among patients with congenital heart defects but is likely an overlooked cause of long-term illness. Objective To study a large national population (n=200) of adults with Fontan circulation and their potential partners regarding. * the prevalence and explanatory factors for sexual dysfunction and infertility in women and men with Fontan circulation (Study A). * the outcomes of pregnancy, choice of delivery mode, and complications in patients with Fontan circulation (Study B). * the experiences and perceptions of becoming parents among women (n=20) and men (n=20), as well as elucidate reasoning and family planning among women and men (n=20) who have not become parents (Study C). * Investigate the prevalence and explanatory factors for (Sub-study D): * Fatigue * In-depth cognitive screening to describe specific cognitive functions such as auditory memory, visuospatial memory, attention, cognitive speed, and executive functions. The aim of this research is to gain more knowledg…

This description comes directly from the study's public registry record.

Talk to the study team

Caroline Lilliecreutz, PhD, Docent  ·  +46708731124  ·  caroline.lilliecreutz@regionostergotland.se

Always discuss trial participation with your own doctor first.

Locations (15)

Lund University Skåne University HospitalLund, Skåne County, SwedenRecruiting
Sahlgrenska Academy, University of Gothenburg Sahlgrenska University HospitalGothenburg, SwedenNot Yet Recruiting
Sahlgrenska University Hospital,Gothenburg, SwedenNot Yet Recruiting
University Hospital, LinköpingLinköping, SwedenNot Yet Recruiting
Skåne University Hospital, Lund UniversityLund, SwedenNot Yet Recruiting
Karolinska University HospitalStockholm, SwedenNot Yet Recruiting
Karolinska University HospitalStockholm, SwedenNot Yet Recruiting
Karolinska University HospitalStockholm, SwedenNot Yet Recruiting
University West, Drottning Silvia's Children's Hospital/Sahlgrenska University Hospital,Trollhättan, SwedenNot Yet Recruiting
Umeå University, Norrland University HospitalUmeå, SwedenNot Yet Recruiting
Umeå University, Norrlands University HospitalUmeå, SwedenNot Yet Recruiting
Umeå University, Norrlands University HospitalUmeå, SwedenNot Yet Recruiting

+ 3 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06258382