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Study identifier: NCT06257758 Synced from ClinicalTrials.gov · July 28, 2026
● Terminated

A Phase 1/2 Study of VIO-01 in Participants With Recurrent Solid Tumors

Condition: Advanced or Metastatic Solid Tumors · Breast Cancer · Recurrent Ovarian Cancer  ·  Sponsor: Valerio Therapeutics

PhasePhase 1/Phase 2
Planned participants6
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this phase 1/2 clinical trial is to investigate the safety of an investigational drug called VIO-01 when taken by people who have different types of solid tumor cancers. There are two parts to this trial, part 1 and part 2. Part 1 of the trial aims to answer these questions: * The safety and tolerability of VIO-01 when it is given alone or in combination with other anti-cancer therapies. * The highest dose that people can take without having unacceptable side effects * How well your body tolerates the drug alone or in combination, how they are absorbed, and the effects they have on your disease. Part 2 of the trial will further test VIO-01's effect in participants with advanced HRRm or HRD+ solid tumors and HRRm/HRD+ recurrent ovarian cancer. Participants will follow a schedule of visits to the study site to have assessments done related to their health condition and to receive the trial treatment.

This description comes directly from the study's public registry record.

Talk to the study team

Contact details are listed per location below or on the registry record.

Always discuss trial participation with your own doctor first.

Locations (3)

Florida Cancer Specialists & Research InstituteLake Mary, Florida, United States
Stephenson Cancer Center - University of OklahomaOklahoma City, Oklahoma, United States
Next OncologySan Antonio, Texas, United States

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Source record: clinicaltrials.gov/study/NCT06257758