Condition: Cancer Surgery · Intraoperative Hypothermia · Targeted Temperature Management · Sponsor: Peking University First Hospital
Intraoperative hypothermia is common in patients having major surgery and the compliance with intraoperative temperature monitoring and management remains poor. Studies suggest that intraoperative hypothermia is an important risk factor of postoperative delirium, which is associated with worse early and long-term outcomes. Furthermore, perioperative hypothermia increases stress responses and provokes immune suppression, which might promote cancer recurrence and metastasis. In a recent trial, targeted temperature management reduced intraoperative hypothermia and emergence delirium. There was also a trend of reduced postoperative delirium, although not statistically significant. This trial is designed to test the hypothesis that intraoperative targeted temperature management may reduce postoperative delirium and improves progression-free survival in older patients recovering from major cancer surgery.
This description comes directly from the study's public registry record.
Dong-Xin Wang, MD, PhD · 8610 83572784 · wangdongxin@hotmail.com
Xin-quan Liang, MD · +8615210846532 · liangxinquan09@163.com
Always discuss trial participation with your own doctor first.
| The People's Hospital of Chizhou | Chizhou, Anhui, China | Not Yet Recruiting |
| The Second Affiliated Hospital of Anhui Medical University | Hefei, Anhui, China | Recruiting |
| The First Affiliated Hospital of Anhui Medical University | Hefei, Anhui, China | Recruiting |
| Maanshan People's Hospital | Ma’anshan, Anhui, China | Recruiting |
| Dongzhimen Hospital Beijing University of Chinese Medicine | Beijing, Beijing Municipality, China | Not Yet Recruiting |
| Peking University First Hospital | Beijing, Beijing Municipality, China | Recruiting |
| Guang'anmen Hospital China Academy of Chinese Medical Sciences | Beijing, Beijing Municipality, China | Recruiting |
| Xiyuan Hospital of China Academy of Chinese Medical Sciences | Beijing, Beijing Municipality, China | Recruiting |
| Peking Union Medical College Hospital | Beijing, Beijing Municipality, China | Recruiting |
| Aerospace Medical Center | Beijing, Beijing Municipality, China | Recruiting |
| Beijing Chao-Yang Hospital, Capital Medical University | Beijing, Beijing Municipality, China | Not Yet Recruiting |
| Beijing Chuiyangliu Hospital | Beijing, Beijing Municipality, China | Not Yet Recruiting |
+ 24 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT06256354