Condition: Severe Aplastic Anemia · Platelet Transfusion Refractoriness · Sponsor: Institute of Hematology & Blood Diseases Hospital, China
Due to long-term dependence on platelet transfusion, some severe aplastic anemia (SAA) patients suffer platelet transfusion refractoriness (PTR). Unlike immune thrombocytopenia (ITP), glucocorticoids and human immunoglobulin (IVIg) are generally ineffective for PTR. Due to the lack of effective intervention methods, patients with PTR suffer increased platelet transfusions, bleeding events and treatment costs, prolonged hospital stays, and decreased survival rate. SAA with PTR has become a challenge for physicians. The experiment aims to explore the efficacy of rituximab in the treatment of SAA with PTR, and establish a new effective, safe treatment method with relatively low treatment cost.
This description comes directly from the study's public registry record.
Huang Jinbo, MD. · +86 22 23909023 · huangjinbo@ihcams.ac.cn
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| Institute of Hematology & Blood Diseases Hospital Chinese Academy of Medical Sciences | Tianjin, Tianjin Municipality, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06254560