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Study identifier: NCT06250023 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

SAVE- Oral Antibiotics for Treatment of Vertebral Osteomyelitis

Condition: Osteomyelitis; Vertebra  ·  Sponsor: Rigshospitalet, Denmark

PhaseN/A
Planned participants530
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Background The current Danish National Guideline for treatment of pyogenic vertebral osteomyelitis (PVO) recommends 6 weeks antibiotic (AB) treatment, with a 2-week intravenous (IV) AB lead-in followed by 4 weeks oral AB for uncomplicated PVO, and 12 weeks AB treatment with a 2-4-week IV AB lead-in followed by 8 weeks oral AB for complicated PVO. The primary objective of the current study is to investigate whether shortening the duration of IV AB to one week for both complicated and uncomplicated PVO is non-inferior to the current Danish National Guideline.

This description comes directly from the study's public registry record.

Talk to the study team

Anne-Mette Lebech, MD  ·  +4535458622  ·  anne-mette.lebech@regionh.dk

Always discuss trial participation with your own doctor first.

Locations (1)

Department of Infectious Diseases, Rigshospitalet, Copenhagen, DenmarkCopenhagen, DenmarkRecruiting

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Source record: clinicaltrials.gov/study/NCT06250023