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Study identifier: NCT06249438 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study of C-CAR168 in the Treatment of Autoimmune Diseases Refractory to Standard Therapy

Condition: Systemic Lupus Erythematosus (SLE) · Immune-mediated Necrotizing Myopathy (IMNM) · Neuromyelitis Optica Spectrum Disorders (NMOSD)  ·  Sponsor: RenJi Hospital

PhasePhase 1
Planned participants30
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

About this study

This is an investigator-initiated, multicenter, open-label study of C-CAR168, an autologous bi-specific CAR-T therapy targeting CD20 and BCMA, for the treatment of adult patients with autoimmune diseases refractory to standard therapy

This description comes directly from the study's public registry record.

Talk to the study team

Nan Shen, MD & PhD  ·  +86-21-63260477  ·  nanshensibs@gmail.com

Huihua Ding, MD  ·  +86-21-53882280  ·  dinghuihua@outlook.com

Always discuss trial participation with your own doctor first.

Locations (1)

Department of Rheumatology, RenJi Hospital, School of Medicine, Shanghai JiaoTong UniversityShanghai, Shanghai Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06249438