Condition: Atrial Fibrillation, Paroxysmal or Persistent · Sponsor: Ratika Parkash
Atrial fibrillation (AF) is a major health problem, with a prevalence of 0.4-1% of the population. It results in high healthcare costs and significant morbidity, especially for patients with severe symptoms. The RASTA-AF randomized control trial (RCT) is designed to answer the following question: does vigorous treatment of AF with aggressive risk factor management plus catheter ablation reduce AF-related outcomes as compared to catheter ablation plus usual care in patients with symptomatic AF and risk factors that promote AF. This study is a multicenter, prospective cohort study that will enrol patients who decline participation in the RASTA-AF RCT but agree to be followed in a registry. The objective of RASTA-Cohort is to determine whether patients who decline participation in the RASTA-AF RCT have different clinical characteristics and quality of life than patients who accept participation in the study, and whether they suffer from worse AF-related outcomes than patients in the RCT.
This description comes directly from the study's public registry record.
Laura Hamilton, BSC, MAHSR · 902 473-7226 · laura.hamilton@nshealth.ca
Karen Giddens · 902 237-5551 · karen.giddens@nshealth.ca
Always discuss trial participation with your own doctor first.
| Foothills Hospital | Calgary, Alberta, Canada | Recruiting |
| QEIIHSC | Halifax, Nova Scotia, Canada | Recruiting |
| London Health Sciences Centre | London, Ontario, Canada | Recruiting |
| University of Ottawa Heart Institute | Ottawa, Ontario, Canada | Recruiting |
| Sunnybrook Hospital | Toronto, Ontario, Canada | Recruiting |
| Montreal Heart Institute | Montreal, Quebec, Canada | Recruiting |
| Regina General Hospital | Regina, Saskatchewan, Canada | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06249269