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Study identifier: NCT06249048 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Phase 1/2 Study of Intratumoral Injection of STX-001 in Advanced Solid Tumors as Monotherapy or in Combination With Pembrolizumab

Condition: Advanced Solid Tumor  ·  Sponsor: Strand Therapeutics Inc.

PhasePhase 1/Phase 2
Planned participants108
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Phase 1/2, Open-label, Multi-center, First-in-human Study of the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Anti-tumor Activity of STX-001 Delivered by Intratumoral Injection in Patients with Advanced Solid Tumors as a Monotherapy or in Combination with Pembrolizumab. The study now includes a monotherapy cohort targeting visceral lesions and a separate Phase 2 monotherapy cohort for advanced melanoma.

This description comes directly from the study's public registry record.

Talk to the study team

S Thomas, MS  ·  617-993-9281  ·  stx001.inquiry@strandtx.us

Always discuss trial participation with your own doctor first.

Locations (7)

HonorHealth Research and Innovation InstituteScottsdale, Arizona, United StatesNot Yet Recruiting
NextGen OncologyBeverly Hills, California, United StatesRecruiting
Cleveland ClinicCleveland, Ohio, United StatesNot Yet Recruiting
University of Pittsburgh Medical CenterPittsburgh, Pennsylvania, United StatesRecruiting
The University of Texas MD Anderson Cancer CenterHouston, Texas, United StatesRecruiting
Huntsman Cancer Institute - University of UtahSalt Lake City, Utah, United StatesNot Yet Recruiting
Melanoma Institute AustraliaWollstonecraft, AustraliaRecruiting

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Source record: clinicaltrials.gov/study/NCT06249048