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Study identifier: NCT06248515 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Phase II Trial of Sacituzumab Govitecan in Patients With Advanced Thymic Epithelial Tumors

Condition: Thymoma · Thymic Carcinoma  ·  Sponsor: Georgetown University

PhasePhase 2
Planned participants18
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to study the effect of sacituzumab govitecan-hziy in adult patients with advanced thymoma and thymic carcinoma after progressing on at least one prior line of therapy. The main question it aims to answer is: • What is the overall response rate (ORR) in patients with advanced thymoma and thymic carcinoma? Participants will: * receive a fixed dose of 10 mg/kg given intravenously, once weekly on Days 1 and 8 of continuous 21-day treatment cycles until disease progression or unacceptable toxicity * have regular blood tests, scans, and examinations to monitor their health. * have blood and a biopsy of their tumor for research purposes.

This description comes directly from the study's public registry record.

Talk to the study team

Chul Kim, MD  ·  202-444-2223  ·  Chul.Kim@gunet.georgetown.edu

Always discuss trial participation with your own doctor first.

Locations (4)

Stanford Cancer InstitutePalo Alto, California, United StatesRecruiting
Lombardi Comprehensive Cancer Center, Georgetown UniversityWashington D.C., District of Columbia, United StatesRecruiting
University of Chicago Medical CenterChicago, Illinois, United StatesRecruiting
John Theurer Cancer Center at Hackensack University Medical CenterHackensack, New Jersey, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06248515